“Large reductions in COVID-19 deaths are possible using ivermectin. Using ivermectin early in the clinical course may reduce numbers progressing to severe disease… Ivermectin is likely to have a significant impact on the SARS-CoV-2 pandemic globally.”

Abstract

Background: 

Repurposed medicines may have a role against the SARS-CoV-2 virus. The antiparasitic ivermectin, with antiviral and anti-inflammatory properties, has now been tested in numerous clinical trials.

Areas of uncertainty: 

We assessed the efficacy of ivermectin treatment in reducing mortality, in secondary outcomes, and in chemoprophylaxis, among people with, or at high risk of, COVID-19 infection.

Therapeutic Advances: 

Meta-analysis of 15 trials found that ivermectin reduced risk of death compared with no ivermectin (average risk ratio 0.38, 95% confidence interval 0.19–0.73; n = 2438; I2 = 49%; moderate-certainty evidence). This result was confirmed in a trial sequential analysis using the same DerSimonian–Laird method that underpinned the unadjusted analysis. This was also robust against a trial sequential analysis using the Biggerstaff–Tweedie method. Low-certainty evidence found that ivermectin prophylaxis reduced COVID-19 infection by an average 86% (95% confidence interval 79%–91%). Secondary outcomes provided less certain evidence. Low-certainty evidence suggested that there may be no benefit with ivermectin for “need for mechanical ventilation,” whereas effect estimates for “improvement” and “deterioration” clearly favored ivermectin use. Severe adverse events were rare among treatment trials and evidence of no difference was assessed as low certainty. Evidence on other secondary outcomes was very low certainty.

Conclusions: 

Moderate-certainty evidence finds that large reductions in COVID-19 deaths are possible using ivermectin. Using ivermectin early in the clinical course may reduce numbers progressing to severe disease. The apparent safety and low cost suggest that ivermectin is likely to have a significant impact on the SARS-CoV-2 pandemic globally.

https://journals.lww.com/americantherapeutics/Fulltext/2021/08000/Ivermectin_for_Prevention_and_Treatment_of.7.aspx

4 thoughts on ““Large reductions in COVID-19 deaths are possible using ivermectin. Using ivermectin early in the clinical course may reduce numbers progressing to severe disease… Ivermectin is likely to have a significant impact on the SARS-CoV-2 pandemic globally.”

  1. The question is of course, how long can the governments and omniscient medical authorities of the post-Christian West continue to ignore, suppress and slander reality? If the last eighteen months is anything to go by, the answer is ‘A lonnnng time.’

  2. My concern is will it help the jabbed? I understand it can’t help heart, brain, clotting etc issues….but the jabbed who have not experienced those side effects, will it be effective for them?

    1. I just read an article 3 days ago that detailed how Dr Robert Malone who pioneered mRNA genetics and has been very vocal about the overall safety of these vaccines has been taking Ivermectin to counter the side effects he experienced from the Moderna jab. Apparently it was something similar to what Eric Clapton experienced but not as severe but still very uncomfortable. It stated Dr Malone travels extensively as a requirement of his job and had no choice but to take it to fulfill his contract obligations. I wish I could find it. If I find it I will post it here.

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