“In this paper, we present the evidence that vaccination, unlike natural infection, induces a profound impairment in type I interferon signaling, which has diverse adverse consequences to human health.”

January 21, 2022

Abstract

The mRNA SARS-CoV-2 vaccines were brought to market in response to the widely perceived public health crises of Covid-19.The utilization of mRNA vaccines in the context of infectious disease had no precedent, but desperate times seemed to call for desperate measures. The mRNA vaccines utilize genetically modified mRNA encoding spike proteins. These alterations hide the mRNA from cellular defenses, promote a longer biological half-life for the proteins, and provoke higher overall spike protein production. However, both experimental and observational evidence reveals a very different immune response to the vaccines compared to the response to infection with SARS-CoV-2. As we will show, the genetic modifications introduced by the vaccine are likely the source of these differential responses. In this paper, we present the evidence that vaccination, unlike natural infection, induces a profound impairment in type I interferon signaling, which has diverse adverse consequences to human health. We explain the mechanism by which immune cells release into the circulation large quantities of exosomes containing spike protein along with critical micro RNAs that induce a signaling response in recipient cells at distant sites. We also identify potential profound disturbances in regulatory control of protein synthesis and cancer surveillance. These disturbances are shown to have a potentially direct causal link to neuro degenerative disease, myocarditis, immune thrombocytopenia, Bell’s palsy, liver disease, impaired adaptive immunity, increased tumorigenesis, and DNA damage. We show evidence from adverse event reports in the VAERS database supporting our hypothesis. We believe a comprehensive risk/benefit assessment of the mRNA vaccines excludes them as positive contributors to public health, even in the context of the Covid-19 pandemic

In this paper we explore the scientific literature suggesting that vaccination with an mRNA vaccine initiates a set of biological events that are not only different from that induced by vaccination but are in several ways demonstrably counterproductive to both short- and long-term immune competence and normal cellular function. These vaccinations have now been shown to downregulate critical pathways related to cancer surveillance, infection control, and cellular homeostasis. They introduce into the body highly modified genetic material. A medRxiv preprint has revealed a remarkable difference between the characteristics of the immune response to an infection with SARS-CoV-2 as compared with the immune response to an mRNA vaccine against COVID-19 [5]. Differential gene expression analysis of peripheral dendritic cells revealed a dramatic upregulation of both type I and type II interferons (IFNs) in COVID-19 patients, but not in vaccinees. One remarkable observation they made was that there was an expansion of circulating hematopoietic stem and progenitor cells (HSPCs) in COVID-19 patients, but this expansion was notably absent following vaccination.A striking expansion in circulating plasmablasts observed in COVID-19 patients was also not seen in the vaccinees. All of these observations are consistent with the idea that the vaccines actively suppress type IIFN signaling, as we will discuss below. In this paper we will be focusing extensively, though not exclusively, on vaccination-induced type I IFN suppression and the myriad downstream effects this has on the related signaling cascade

https://www.researchgate.net/publication/357994624_Innate_Immune_Suppression_by_SARS-CoV-2_mRNA_Vaccinations_The_role_of_G-quadruplexes_exosomes_and_microRNAs

8 thoughts on ““In this paper, we present the evidence that vaccination, unlike natural infection, induces a profound impairment in type I interferon signaling, which has diverse adverse consequences to human health.”

  1. And yet the believers will double down on stupid. Bank on that. It’s a cult I tell you.

    1. It’s scary. I have a friend who got covid, his wife got covid twice, hospitalized twice… Who also developed blood clots… Kids got covid… Son’s friend 20yo dead of brain aneurysm…ALL VACCINATED

      Yet he still insists vaccine worked because he didn’t die.

      This has been a real struggle for me because at times I get filled with such anger at my own family and friends! Why am I getting angry for them when they should be the ones getting angry that they were scammed? Why is not one vaccinated waking up?

      And it sickens me that in order to be proven right, people have to suffer. I really do hope I wandered too far down a rabbit hole and this all turns into conspiracy and I come out looking foolish. I can handle it. But unfortunately the more evidence that comes out, the more it’s looking like things are as bad as has been predicted.

      Maybe this is how Mary’s Immaculate Heart will triumph? When all hope is lost for these people and civilizations are collapsing and no vaccine, scientist, or government official can help them, maybe Christ starts working miracles through the rosary.

  2. AIDS: “Acquired immunodeficiency syndrome (AIDS) is a chronic, potentially life-threatening condition caused by the human immunodeficiency virus (HIV). By damaging your immune system, HIV interferes with your body’s ability to fight infection and disease.”

    VAIDS: Immunodefficiency is simulated, and introduced, by design, to “interfere with and inhibit your body’s ability to fight infection and disease” (not just CV … but all disease).

    They have infected the world with AIDS.

    Who would do such a thing? Hint: those who explicitly worship and follow he who caused Pope St. Leo XIII to faint at the vision of what was to come. We have heard rumors of these things. They are undoubtedly true.

    I, for one, am tired of playing defense. The collapse in the secular world started with the collapse within our Church – we ARE the leaven; the conduit between heaven and earth. The restoration begins with Catholics. We must reclaim the Papacy as ONE, and then reclaim ALL Catholics as “Trads”, unified under ONE Liturgical formula – which is the Holy Sacrifice of Pope St Pius V, Trent and Quo Primum.

    I truly believe the dark powers that release evil forces like this can ONLY be restrained by the “prayer and fasting” (Matt 17:21) of a Church united with Christ through the eternal Magisterium once again.

    1. As the paper states in its summary (excellent find, btw):

      “… we present the evidence that vaccination, unlike natural infection, induces a profound impairment in type I interferon signaling, which has diverse adverse consequences to human health.”

      “We explain the mechanism by which immune cells release into the circulation large quantities of exosomes containing spike protein along with critical micro RNAs that induce a signaling response in recipient cells at distant sites.”

      “We also identify potential profound disturbances in regulatory control of protein synthesis and cancer surveillance. These disturbances are shown to have a potentially direct causal link to neuro degenerative disease, myocarditis, immune thrombocytopenia, Bell’s palsy, liver disease, impaired adaptive immunity, increased tumorigenesis, and DNA damage.”

  3. I’m a cynic. Unless the media says this is true, most people who have been vaxxed will reject it.
    We live in a clown world where even the words meaning fully vaccinated have now been “pivoted” by Walensky at the CDC. You now must have your booster to be “fully vaccinated”. Watch all the sheep trip over themselves to get the booster, regardless of the 400 athletes dropping dead, the numbers getting myocarditis, even little children, dying of cardiac arrest one day after the jab. No matter. The sheep will line up until…the media says not to. Coercion works. Censorship works. Not on everybody, but many.

  4. Last week I saw on my co-worker’s calendar that he had scheduled his “booster” shot. This man is forty something with an MBA, so educated but imo lacking common sense. I don’t know what got into me but I decided to ask him. I said “I know I’m probably overstepping, but you’re a vegan who is so careful about what you put in your body. Why are you getting this booster when it obviously isn’t working?” His answer to me was “yes, you’re overstepping.” They can’t see what we see. It’s frustrating.

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